EACS2023: 784 Insufficient vaccine coverage and vaccine hesitancy in people living with HIV: a prospective study in out-patient clinics of the Parisian region A. Kolakowska , E. Marshall , E. Krastinova , D. Salmon , A. Cros , P. Sagot , A. Chéret Bastia Hospital, Bastia, France, Pitié Salpêtrière University Hospital, Paris, France, Créteil Hospital, Paris, France, University of Paris/Fournier Institut, Paris, France, Hôtel Dieu University Hospital, Paris, France, Gouadeloupe University Hospital, Pointe-à-Pitre, France General data Abstract category: Access and delivery of care Abstract body Purpose: Vaccine prevention strategies play a crucial role in care offered to people living with HIV (PLWHA). In 2014 French Public Health Council (HCSP) published updated vaccine guidelines for PLWHA. The aim of this study was to assess immunization coverage in PLWHA in Paris area 9 years after the recommendations were provided and to identify barriers to vaccination. Method: A cross-sectional survey was conducted among a random sample of PLWHA in 16 hospitals in Paris area between February 2020 and April 2021. The vaccination status, characteristics, opinions and attitudes of participants were collected through a face-to-face questionnaire and from medical records. Results: Three hundred thirty-eight PLWHA were included, with a median age of 51 years (IQR: 42-58) and majority of male (64.1%). Twenty-one (6.2%) of the participants had hepatitis B co-infection. Vaccination coverage is presented in Figure 1. The main reasons for vaccine reluctance were by decreasing order: lack of vaccine recall by caregivers, fear of injections, conviction of having a contraindication to vaccines, belief that vaccines are purposeless or harmful. The overall willingness to get vaccinated was 71.0% (95%CI: 65,9%-75,8%). In multivariate analysis multiple factors were associated with higher vaccine uptake; for dTP vaccine: higher education level (p=0.0014), having vaccination records (p<0.0001) and having a family doctor (p=0.0078); for seasonal influenza vaccine: age over 60 years (p=0.0327), higher education level (p=0.0126), being employed (p=0.0049); for hepatitis A vaccine: men having sex with men transmission mode (p=0.0247). Conclusions: The overall vaccine coverage was suboptimal for all the recommended vaccines in PLWHA. Patients’ willingness to get vaccinated was encouraging. Modifiable factors to increase vaccination coverage were identified. Our results may help developing strategies for better vaccine adherence. General conditions 1. I confirm that I previewed this abstract and that all information is correct. I accept that the content of this abstract cannot be modified or corrected after the submission deadline and I am aware that it will be published exactly as submitted.: Yes 2. I confirm that the submission of the abstract constitutes my consent to publication (e.g. conference website, programmes, other promotions, etc.). : Yes 3. I herewith confirm that the contact details saved in this system are those of the corresponding author, who will be notified about the status of the abstract. The corresponding author is responsible for informing the other authors about the status of the abstract.: Yes 4. I agree that all data provided may be used (saved, stored, processed, transmitted and deleted) in compliance with the privacy policy to provide the services described.: Yes 1 2 3 4 5 5 6 1 2 3 4 5 6 47
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