International Society for Pediatric and Adolescent Diabetes
ISPAD 2014 | 40th Anniversary |
243
P155
Type 1 diabetes mellitus and precocios puberty: rare association
M. Bessahraoui
1
, S. Niar
1
, M. Naceur
1
, A. Zennaki
1
, K. Bouziane-Nedjadi
1
1
Faculty of Medicine of Oran, Oran, Algeria
Precocious puberty is defined as pubertal development that begins at an earlier age than expected;
most pediatric endocrinology subspecialists use cutoff ages of 8 years for girls and 9 years for boys.
We reported in this case, rare association between type 1 diabetes mellitus and precocios puberty.
We present a girl with type 1 diabetes developed at the age of 3 years, with good glycemic control
using insulin. She also had a developmental.
At the age of 6 years child had breast enlargement, height increase, and an increase in growth
velocity. On examination, she was found to have Tanner stage 3 breast development, and her vaginal
mucosa was estrogenized. Her height was above the 97th percentile. Biochemically, she was
diagnosed as having central precocious puberty, and magnetic resonance imaging of her pituitary
gland diagnosed central precocious puberty idiopathic. Treatment with leuprolide resulted in
normalization of her growth rate and regression of the breast development; the vaginal mucosa also
became unestrogenized.
Conclusion:
Precocious puberty and type 1 diabetes is a rare association. the relationship has not
been determined.
