ECFS 2020 - Optimizing pharmaceutical care in cystic fibrosis

2  www.ecfs.eu OPTIMIZING PHARMACEUTICAL CARE IN CYSTIC FIBROSIS CONTENTS CONTENTS List of contributors ................................................................................................................................................................................................................ 4 Preface Isabelle Fajac ............................................................................................................................................................................................................ 9 Introduction Siân Bentley, Carlo Castellani, Daniel Peckham, Nicola Shaw ......................................... 11 Chapter 1 The role of medicines in changing the clinical history of Cystic Fibrosis .................................................................................................................................................................................................................... 13 Jim Littlewood, Daniel Peckham Chapter 2 Cystic Fibrosis Medication: present and future ................................................................................ 33 Siân Bentley, Daniel Peckham, Carlo Castellani, Nicola Shaw Chapter 3 Pharmacokinetics/pharmacodynamics guided approach to antibacterial administration in cystic fibrosis .............................................................................................................. 45 Elio Castagnola, Giuliana Cangemi, Alessio Mesini, Francesca Mattioli Chapter 4 Treatment challenges associated with drug-drug interactions in cystic fibrosis ....................................................................................................................................................................................................................... 65 Olivia K. Paulin, Elena K. Schneider-Futschik Chapter 5 The role of the CF specialist pharmacist in everyday practice and in clinical trials ......................................................................................................................................................................................................................... 85 Amanda Bevan, Elaine Bowman Chapter 6 Parenteral administration in hospital and at home: challenges and solutions ...................................................................................................................................................................................... 101 Edwin Brokaar, Nichola MacDuff, Lisa Sammons, Silvia Gartner, Erik Wilms, Douglas McCabe Chapter 7 Aerosol therapy for CF lung disease: the basics ....................................................................... 119 Hettie M. Janssens, Harm A.W.M. Tiddens Chapter 8 CF medicines in children .................................................................................................................................................... 139 Michaela Semeraro, Kate Hayes, Isabelle Sermet-Gaudelus