ECFS 2020 - Optimizing pharmaceutical care in cystic fibrosis

114    www.ecfs.eu OPTIMIZING PHARMACEUTICAL CARE IN CYSTIC FIBROSIS PARENTERAL ADMINISTRATION: CHALLENGES AND SOLUTIONS CHAPTER 6 4 Summary CF patients frequently receive IV antibiotic treatment for PEx. These treatments have a major impact on daily life, but are necessary to maintain health. Many antibiotics used to treat persons with CF can be administered either the hospital or at home, and the latter option is usually preferred. The choice of line used depends on patient characteris- tics, patient preferences, and care facilities. Most antibiotics can be prepared for infu- sion by both the patient and caregiver or provided as a ready-made infusion. In both cases, thorough instruction and training are required to ensure safe administration, and patients should have 24/7 access to health- care providers for support. social functioning, and role disabilities due to emotional problems. A Greek study assessed QoL in 35 stable pediatric CF patients colonized with P. aeruginosa and treated with IV anti- biotics for 2 weeks either in hospital or at home [23]. QoL was measured using the DISABKIDS questionnaire (condi- tion-specific module for CF), a validated questionnaire completed by children and their parents. In the home group signifi- cant improvements were observed in all QoL domains, while in the hospital group significant improvements were observed only in physical and impact domains. More- over, home treatment was associated with substantial economic savings as compared with hospital treatment.